Collateral Blood Flow and Myocardial Viability

Jan J. Piek, Peter J. Sabia, Eric R. Powers, Sanjiv Kaul

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: Sabia et al. (Dec. 24 issue)1 used myocardial contrast echocardiography to assess collateral flow, on the basis of experimental validation studies. The accuracy of this method in determining collateral flow in humans with chronic coronary occlusion has, to my knowledge, never been demonstrated. Nevertheless, total occlusion of a coronary artery is a “stable” coronary condition that would have allowed a comparison of the distribution of the microbubbles in collateral-dependent areas with the results of other techniques for the assessment of myocardial flow, such as perfusion scintigraphy. The choice of angiographic grading of collateral vessels is unclear and…

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number21
StatePublished - May 27 1993
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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