Abstract
Background: Liver biopsy through endoscopic ultrasound (EUS)has become a novel approach for tissue acquisition. We aim to evaluate the adequacy of EUS-guided liver biopsies in comparison to those obtained through interventional radiology (IR)techniques. Methods: A retrospective single-center analysis was performed of all IR (transjugular or image-guided percutaneous)and EUS-guided liver biopsies performed at an academic medical center from January 2016 to January 2018. Patient demographics, histologic characteristics, and clinical outcomes were collected. Results: 152 procedures were included for analysis. 45% of liver biopsies were performed through EUS-guidance. The most common indication for liver biopsy was NASH fibrosis staging (n = 64). IR-guided biopsies contained a higher number of complete portal triads (13.6 vs. 10.8 p ≤ 0.01)while EUS-guided biopsies produced an increased total specimen length (4.6 cm vs. 3.6 cm p ≤ 0.01).47% of biopsy samples were fragmented with the majority of these (72%)occurring with EUS-guided procedures (p ≤ 0.01). IR-guided biopsies led to more complications in comparison to EUS-guided procedures (p = 0.03)Conclusion: Liver biopsies performed through EUS-guidance are comparable to IR-guided liver biopsies and may have an enhanced safety profile with acceptable tissue acquisition characteristics. Standardization of techniques and needles is needed for optimization of tissue sampling.
Original language | English (US) |
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Pages (from-to) | 826-830 |
Number of pages | 5 |
Journal | Digestive and Liver Disease |
Volume | 51 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2019 |
Keywords
- Complications
- Liver biopsy
- Tissue adequacy
ASJC Scopus subject areas
- Hepatology
- Gastroenterology