Comparison of neurocognitive outcomes after carotid endarterectomy and carotid artery stenting

Jerry J. Kim, Samuel Schwartz, Johnny Wen, Christian De Virgilio, Abeline Lobue, Irwin Walot, Matthew Koopmann, Carlos Donayre, Rodney A. White

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Cognitive and emotional outcomes after carotid endarterectomy (CEA) and carotid artery stenting with embolic protection device (CAS + EPD) are not clear. Patients were entered prospectively into a United States Food and Drug Administration.approved singlecenter physiciansponsored investigational device exemption between 2004 and 2010 and received either CEA or CAS + EPD. Patients underwent cognitive testing preprocedure and at 6, 12, and 60 months postprocedure. Cognitive domains assessed included attention, memory, executive, motor function, visual spatial functioning, language, and processing speed. Beck Depression and anxiety scales were also compared. There were a total of 38 patients that met conventional indications for carotid surgery (symptomatic with .50% stenosis or asymptomatic with .70% stenosis).12 patients underwent CEA, whereas 26 patients underwent CAS + EPD. Both CEA and CAS + EPD patients showed postprocedure improvement in memory and executive function. No differences were seen at followup in regards to emotional dysfunction (depression and anxiety), attention, visual spatial functioning, language, motor function, and processing speed. Only two patients underwent neuropsychiatric testing at 60 months.these CAS + EPD patients showed sustained improvement in memory, visual spatial, and executive functions. In conclusion, cognitive and emotional outcomes were similar between CEA and CAS + EPD patients.

Original languageEnglish (US)
Pages (from-to)1010-1014
Number of pages5
JournalAmerican Surgeon
Issue number10
StatePublished - Oct 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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