Conditions for optic axon outgrowth

R. D. Lund, M. H. Hankin, A. J. Seflon, V. H. Perry

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


A series of studies is described which show that retinai axon outgrowth can be stimulated by the close proximity of an appropriate target region. The suggestion is offered that, in normal development, optic axons first follow cues available at the surface of the brainstem, but once they reach a target region, ramify there in response to the presence of a target-derived factor.

Original languageEnglish (US)
Pages (from-to)218-226
Number of pages9
JournalBrain, Behavior and Evolution
Issue number4
StatePublished - 1988
Externally publishedYes


  • Axonal guidance
  • Neural transplants
  • Visual system

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Behavioral Neuroscience


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