TY - JOUR
T1 - Conservative management of pituitary macroadenoma contacting the optic apparatus
AU - Won, Won Hyung
AU - Tam, Samantha
AU - Rotenberg, Brian
AU - Labib, Mohamed Ahmed
AU - Lee, Donald
AU - Nicolle, David A.
AU - Uum, Stan Van
AU - Duggal, Neil
PY - 2010/11/1
Y1 - 2010/11/1
N2 - Objectives: To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway. Design: Retrospective case-series. Setting: Tertiary-care academic institution. Participants: Six patients with diagnosis of NFMA. Main Outcome: Visual function and radiological characteristics of the optic apparatus and pituitary tumor. Results: All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during followup (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision. Conclusions: Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.
AB - Objectives: To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway. Design: Retrospective case-series. Setting: Tertiary-care academic institution. Participants: Six patients with diagnosis of NFMA. Main Outcome: Visual function and radiological characteristics of the optic apparatus and pituitary tumor. Results: All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during followup (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision. Conclusions: Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.
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U2 - 10.1017/s0317167100051532
DO - 10.1017/s0317167100051532
M3 - Article
C2 - 21059548
AN - SCOPUS:79952943489
SN - 0317-1671
VL - 37
SP - 837
EP - 842
JO - Canadian Journal of Neurological Sciences
JF - Canadian Journal of Neurological Sciences
IS - 6
ER -