Conservative management of pituitary macroadenoma contacting the optic apparatus

Won Hyung Won, Samantha Tam, Brian Rotenberg, Mohamed Ahmed Labib, Donald Lee, David A. Nicolle, Stan Van Uum, Neil Duggal

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Objectives: To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway. Design: Retrospective case-series. Setting: Tertiary-care academic institution. Participants: Six patients with diagnosis of NFMA. Main Outcome: Visual function and radiological characteristics of the optic apparatus and pituitary tumor. Results: All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during followup (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision. Conclusions: Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.

Original languageEnglish (US)
Pages (from-to)837-842
Number of pages6
JournalCanadian Journal of Neurological Sciences
Issue number6
StatePublished - Nov 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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