Controversies in preterm brain injury

Anna A. Penn; Pierre Gressens; Bobbi Fleiss; Stephen A. Back; Vittorio Gallo

doi:10.1016/j.nbd.2015.10.012

Controversies in preterm brain injury

Anna A. Penn, Pierre Gressens, Bobbi Fleiss, Stephen A. Back, Vittorio Gallo

Pediatrics

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

Abstract

In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

Original language	English (US)
Pages (from-to)	90-101
Number of pages	12
Journal	Neurobiology of Disease
Volume	92
Issue number	Part A
DOIs	https://doi.org/10.1016/j.nbd.2015.10.012
State	Published - 2016

Keywords

Brain development
Neuroimaging
Preterm brain injury
White matter injury

ASJC Scopus subject areas

Neurology

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10.1016/j.nbd.2015.10.012

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title = "Controversies in preterm brain injury",

abstract = "In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.",

keywords = "Brain development, Neuroimaging, Preterm brain injury, White matter injury",

author = "Penn, {Anna A.} and Pierre Gressens and Bobbi Fleiss and Back, {Stephen A.} and Vittorio Gallo",

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AU - Penn, Anna A.

AU - Gressens, Pierre

AU - Fleiss, Bobbi

AU - Back, Stephen A.

AU - Gallo, Vittorio

PY - 2016

Y1 - 2016

N2 - In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

AB - In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

KW - Brain development

KW - Neuroimaging

KW - Preterm brain injury

KW - White matter injury

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U2 - 10.1016/j.nbd.2015.10.012

DO - 10.1016/j.nbd.2015.10.012

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AN - SCOPUS:84979072415

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SP - 90

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JO - Neurobiology of Disease

JF - Neurobiology of Disease

IS - Part A

ER -

Controversies in preterm brain injury

Abstract

Keywords

ASJC Scopus subject areas

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