Crohn's disease with ovarian granuloma: A case report and review of the literature

We present an interesting case of a 35-year-old nulligravida with Crohn's disease with ovarian involvement. This is a rare manifestation of Crohn's disease, felt to arise from fistulization between the ovary and the intestine, most commonly the ileum. Our review of the literature revealed 11 additional case reports published in English with a total of 15 cases. The mean age at time of presentation was 33.7 years, with a predominance of right-sided involvement. This series included 10 patients with affected right ovaries, 3 with affected left ovaries, and 2 with bilateral involvement. We conclude that ovarian involvement in Crohn's disease, although rare, can exist, and that the gynecologic surgeon should be aware of this relevant disease manifestation.