Cryosurgical treatment of ocular squamous cell carcinoma of cattle

H. E. Farris, F. T. Fraunfelder

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


A total of 718 ocular squamous cell carcinomas of cattle were treated with various cryosurgical units and techniques during a 2.5 year study. In 609 of the lesions, a single freeze was used, with a cure rate (total regression) of 66%. In 109 lesions treated with a double freeze thaw cycle (rapid freeze to -25C, and unaided thaw followed immediately by refreezing to -25C), the cure rate was 97%. Cryosurgical units designed for delivery of liquid nitrogen provided a more rapid rate of freezing and, thus, a higher cure rate than did units designed for delivery of nitrogen vapor. It was concluded that: cryosurgery for treatment of squamous cell carcinoma is a simple and rapid procedure; is economical; provides analgesia itself, due to sensory nerve injury; requires minimal preoperative and no postoperative medications; causes minimal side effects; may be repeated; and is excellent for use on suspect premalignant lesions.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalJournal of the American Veterinary Medical Association
Issue number3
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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