Depression in patients being evaluated for heart transplantation

Robert A. Maricle, Jeffrey D. Hosenpud, Douglas J. Norman, Ann Woodbury, George A. Pantley, Adnan M. Cobanoglu, Albert Starr

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


In the evaluation of 68 consecutive heart transplant candidates, 37 (54%) had one or more depressive syndromes. Premorbid psychiatric risk factors of depression were prevalent throughout the group. Statistically significant associations with depression were found with age, educational and occupational levels, and a history of past depressive episodes, but not with family psychiatric history, parental loss in childhood, history of serious childhood illness, or history of substance abuse. Of the 43 patients transplanted, 16 of 22 who were depressed preoperatively required psychiatric intervention postoperatively compared to 8 of 21 who were not depressed; 75% had a beneficial response to treatment. We recommend that a diagnosis of depression not be considered reason to exclude otherwise suitable candidates for cardiac transplantation.

Original languageEnglish (US)
Pages (from-to)418-424
Number of pages7
JournalGeneral Hospital Psychiatry
Issue number6
StatePublished - Nov 1989

ASJC Scopus subject areas

  • Psychiatry and Mental health


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