@article{b0b3e72689724c719aedb1e0679f4a35,
title = "Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)",
abstract = "Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.",
keywords = "Airway management, Cardiopulmonary arrest, Clinical trials, Emergency medical services, Intubation (intratracheal), Resuscitation",
author = "Wang, {Henry E.} and Prince, {David K.} and Stephens, {Shannon W.} and Heather Herren and Mohamud Daya and Neal Richmond and Jestin Carlson and Craig Warden and Colella, {M. Riccardo} and Ashley Brienza and Aufderheide, {Tom P.} and Idris, {Ahamed H.} and Robert Schmicker and Susanne May and Graham Nichol",
note = "Funding Information: This work is supported by UH2/UH3-HL125163 from the National Heart, Lung and Blood Institute (NHLBI). In addition, the ROC data coordinating center and sites are supported through a series of cooperative agreements through the NHLBI (5U01 HL077863-University of Washington Data Coordinating Center, HL077866-Medical College of Wisconsin, HL077871-University of Pittsburgh, HL077873-Oregon Health and Science University, HL077881-University of Alabama at Birmingham, HL077887-University of Texas Southwestern Medical Center/Dallas). Funding Information: This work is supported by UH2/UH3-HL125163 from the National Heart, Lung and Blood Institute (NHLBI). In addition, the ROC data coordinating center and sites are supported through a series of cooperative agreements through the NHLBI (5U01 HL077863-University of Washington Data Coordinating Center, HL077866-Medical College of Wisconsin, HL077871-University of Pittsburgh, HL077873-Oregon Health and Science University, HL077881-University of Alabama at Birmingham, HL077887-University of Texas Southwestern Medical Center/Dallas). Publisher Copyright: {\textcopyright} 2016 Elsevier Ireland Ltd.",
year = "2016",
month = apr,
day = "1",
doi = "10.1016/j.resuscitation.2016.01.012",
language = "English (US)",
volume = "101",
pages = "57--64",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",
}