Development of a model-based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy

Mathematics

• Simulation Platform 100%
• Optimise 54%
• Clinical Trials 49%
• Model-based 46%
• Design 32%
• Progression 24%
• Critical Path 16%
• Pediatrics 15%
• Inclusion-exclusion 14%
• Qualification 13%
• Mixed Effects 13%
• Nonlinear Effects 13%
• Pathway 12%
• Therapy 11%
• Medicine 11%
• Drugs 10%
• Walk 10%
• Model 10%
• Continuum 9%
• Methodology 7%
• Observation 6%
• Modeling 6%
• Simulation 6%

Medicine & Life Sciences

• Duchenne Muscular Dystrophy 61%
• Clinical Trials 33%
• X-Linked Genetic Diseases 25%
• Disease Progression 20%
• Datasets 20%
• Critical Pathways 15%
• Vital Capacity 14%
• Growth and Development 13%
• United States Food and Drug Administration 12%
• Patient Selection 11%
• Pediatrics 8%
• Therapeutics 2%

Engineering & Materials Science

• Simulation platform 57%
• Pediatrics 14%
• Medicine 10%
• Computer simulation 5%