Directed hybridization of DNA derivatized nanoparticles into higher order structures

Dietrich A. Dehlinger, Benjamin D. Sullivan, Sadik Esener, Michael J. Heller

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Electric field directed hybridization was used to produce twenty layer nanostructures composed of DNA derivatized nanoparticies. Using an electronic microarray device, DNA nanoparticles could be directed and concentrated such that rapid and specific hybridization occurs only on the activated sites. Nanoparticle layers were formed within 30 s of activation and twenty layer structures completed in under an hour. Results demonstrate a unique combination of bottom-up and top-down techniques for nanofabrication.

Original languageEnglish (US)
Pages (from-to)4053-4060
Number of pages8
JournalNano Letters
Issue number11
StatePublished - Nov 2008
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics
  • Mechanical Engineering


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