Discontinuing clozapine: An example of explicit health care rationing

Bentson H. McFariand

doi:10.1007/BF00707496

Discontinuing clozapine: An example of explicit health care rationing

Bentson H. McFariand

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Clozapine's efficacy, side effect profile, and cost raise numerous clinical, administrative, and ethical concerns. The author presents mathematical models to determine the optimal time for an efficacy evaluation. The models are based on the presumption that clinical considerations as well as limited resources will preclude treating for an indefinite length of time a person who has not shown improvement. This quantitative approach to decision making also suggests what types of data should be obtained in future research on clozapine.

Original language	English (US)
Pages (from-to)	399-416
Number of pages	18
Journal	Administration and Policy in Mental Health
Volume	19
Issue number	6
DOIs	https://doi.org/10.1007/BF00707496
State	Published - Jul 1992
Externally published	Yes

ASJC Scopus subject areas

Phychiatric Mental Health
Health Policy
Public Health, Environmental and Occupational Health
Psychiatry and Mental health

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10.1007/BF00707496

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abstract = "Clozapine's efficacy, side effect profile, and cost raise numerous clinical, administrative, and ethical concerns. The author presents mathematical models to determine the optimal time for an efficacy evaluation. The models are based on the presumption that clinical considerations as well as limited resources will preclude treating for an indefinite length of time a person who has not shown improvement. This quantitative approach to decision making also suggests what types of data should be obtained in future research on clozapine.",

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AB - Clozapine's efficacy, side effect profile, and cost raise numerous clinical, administrative, and ethical concerns. The author presents mathematical models to determine the optimal time for an efficacy evaluation. The models are based on the presumption that clinical considerations as well as limited resources will preclude treating for an indefinite length of time a person who has not shown improvement. This quantitative approach to decision making also suggests what types of data should be obtained in future research on clozapine.

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Discontinuing clozapine: An example of explicit health care rationing

Abstract

ASJC Scopus subject areas

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