Abstract
(Chemical Equation Presented) Are you too small? The small molecule (M W=297) shown here was discovered to be an inhibitor of the KIX-KID interaction by using a novel Renilla luciferase complementation assay. This compound also inhibits CREB-mediated gene transcription in living cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2721-2724 |
| Number of pages | 4 |
| Journal | ChemBioChem |
| Volume | 10 |
| Issue number | 17 |
| DOIs | |
| State | Published - Nov 23 2009 |
Keywords
- CREB
- Inhibitors
- Protein complementation
- Protein-protein interactions
- Transcription
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Organic Chemistry