Abstract
We evaluated the association of baseline prognostic factors with conditional net survival among survivors of six subtypes non-Hodgkin lymphoma using the SEER program data from 2000-2012. Among 2-year survivors, further prognosis markedly improved in Burkitts (BL) and diffuse large B-cell lymphoma (DLBCL), and became the same as for follicular lymphoma (5-year net survival ≥ 85%). Mantle cell lymphoma (MCL) demonstrated the worst prognosis of all studied histologies up to 5 years of survivorship. Age and stage lost prognostic significance in BL within 2 years from diagnosis. Racial disparities in net survival disappeared within 2 years for all subtypes, except in chronic lymphocytic leukemia, where black patients had persistently worse prognosis, and in MCL, where they had unexpectedly better prognosis than other races after 2 years. Many baseline factors may lose their initial prognostic value for lymphoma survivors, which should be considered when counseling patients about their prognosis and long-term surveillance.
Original language | English (US) |
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Pages (from-to) | 676-684 |
Number of pages | 9 |
Journal | Leukemia and Lymphoma |
Volume | 57 |
Issue number | 3 |
DOIs | |
State | Published - Mar 3 2016 |
Externally published | Yes |
Keywords
- Burkitt lymphoma
- Conditional survival
- Diffuse large B-cell lymphoma
- Epidemiology
- Non-Hodgkin lymphoma
- Relative survival
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research