Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

Daniel M. Gibbs

doi:10.1016/0024-3205(84)90241-8

Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

Daniel M. Gibbs

Research output: Contribution to journal › Article › peer-review

223 Scopus citations

Abstract

Oxytocin (OT), vasopressin (AVP), and corticotropin (ACTH) levels were measured in peripheral plasma of male rats subjected to one of three models of stress: restraint, cold, or ether. ACTH secretion was increased in all three groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether but not cold. AVP secretion was increased only by ether stress. The data suggest that the hypothalamic and neurohypophysial contribution to the control of ACTH secretion may vary in response to different types of stress.

Original language	English (US)
Pages (from-to)	487-491
Number of pages	5
Journal	Life Sciences
Volume	35
Issue number	5
DOIs	https://doi.org/10.1016/0024-3205(84)90241-8
State	Published - Jul 30 1984
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Pharmacology, Toxicology and Pharmaceutics(all)

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10.1016/0024-3205(84)90241-8

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title = "Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress",

abstract = "Oxytocin (OT), vasopressin (AVP), and corticotropin (ACTH) levels were measured in peripheral plasma of male rats subjected to one of three models of stress: restraint, cold, or ether. ACTH secretion was increased in all three groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether but not cold. AVP secretion was increased only by ether stress. The data suggest that the hypothalamic and neurohypophysial contribution to the control of ACTH secretion may vary in response to different types of stress.",

author = "Gibbs, {Daniel M.}",

note = "Funding Information: Thls work was supported in part by a Mellon Foundatlon Faculty Scholar Award and by NIH grant AM-32517. I would like to thank S. S1merson for sklll-ful technical asslstance, K. Watts for preparing the manuscrlpt, and Dr. S.S.C. Yen for support and encouragement.",

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doi = "10.1016/0024-3205(84)90241-8",

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T1 - Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

AU - Gibbs, Daniel M.

N1 - Funding Information: Thls work was supported in part by a Mellon Foundatlon Faculty Scholar Award and by NIH grant AM-32517. I would like to thank S. S1merson for sklll-ful technical asslstance, K. Watts for preparing the manuscrlpt, and Dr. S.S.C. Yen for support and encouragement.

PY - 1984/7/30

Y1 - 1984/7/30

N2 - Oxytocin (OT), vasopressin (AVP), and corticotropin (ACTH) levels were measured in peripheral plasma of male rats subjected to one of three models of stress: restraint, cold, or ether. ACTH secretion was increased in all three groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether but not cold. AVP secretion was increased only by ether stress. The data suggest that the hypothalamic and neurohypophysial contribution to the control of ACTH secretion may vary in response to different types of stress.

AB - Oxytocin (OT), vasopressin (AVP), and corticotropin (ACTH) levels were measured in peripheral plasma of male rats subjected to one of three models of stress: restraint, cold, or ether. ACTH secretion was increased in all three groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether but not cold. AVP secretion was increased only by ether stress. The data suggest that the hypothalamic and neurohypophysial contribution to the control of ACTH secretion may vary in response to different types of stress.

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ER -

Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress

Abstract

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