Abstract
Objective: To determine the effectiveness of a novel algorithm based on fetal fibronectin (FFN) for management of preterm labor (PTL). Methods: A randomized trial was performed on patients who presented with symptoms of PTL at 24-34 weeks. Patients were randomized to algorithms with cervical exams only versus cervical exams plus FFN. In this algorithm, physicians had to discharge patients with a negative FFN result. The primary outcome was the evaluation time for triage. The secondary outcomes were admission to the hospital for PTL, preterm birth <34 weeks and preterm birth <37 weeks. Results: A total of 76 patients were enrolled and randomized (control n=32, FFN n=44). There were no differences in triage time, hospital admissions or preterm deliveries (PTDs) between the two groups. Conclusion: An algorithm based on FFN for management of PTL does not reduce evaluation times for triage, hospital admissions or PTDs.
Original language | English (US) |
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Pages (from-to) | 706-709 |
Number of pages | 4 |
Journal | Journal of Maternal-Fetal and Neonatal Medicine |
Volume | 26 |
Issue number | 7 |
DOIs | |
State | Published - May 2013 |
Keywords
- Algorithm
- Evaluation time
- Fetal fibronectin
- Preterm labor
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology