TY - JOUR
T1 - Effect of photodynamic therapy for the treatment of halitosis in adolescents – a controlled, microbiological, clinical trial
AU - Costa da Mota, Ana Carolina
AU - França, Cristiane Miranda
AU - Prates, Renato
AU - Deana, Alessandro Melo
AU - Costa Santos, Larissa
AU - Lopes Garcia, Rubia
AU - Leal Gonçalves, Marcela Letícia
AU - Mesquita Ferrari, Raquel Agnelli
AU - Porta Santos Fernandes, Kristianne
AU - Kalil Bussadori, Sandra
N1 - Publisher Copyright:
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Halitosis can exert a negative influence on the social relations of adolescents and affect one's self-image. The aim of this study was to evaluate the clinical and microbiological effect of antimicrobial photodynamic therapy (aPDT) on halitosis in adolescents. Forty-six individuals aged 12 to 19 years were randomly allocated: Group 1 – treatment with photodynamic therapy; Group 2 – treatment with a tongue scraper and Group 3 – treatment with a tongue scraper and photodynamic therapy. The count of bacterial colony-forming units per milliliter was used for the microbiological analysis. Statistical analysis involved the Kruskal–Wallis test followed by the Student–Newman–Keuls test. ANOVA was used for the determination of colony-forming units after treatment. The level of significance for all statistical tests was 5% (p < 0.05). After treatment, a statistically significant reduction in total volatile sulfur compounds was found in all groups (p < 0.001), with the largest reduction (median: 0) found in Group 3 (tongue scraper and photodynamic therapy). Moreover, a statistically significant difference was found between treatment with aPDT and a tongue scraper alone (p < 0.001). The present findings demonstrate an option for the treatment of halitosis in adolescents, with an immediate effect and without the mechanical aggression to the toungue. (Figure presented.) Clinical Trials: NCT02007993.
AB - Halitosis can exert a negative influence on the social relations of adolescents and affect one's self-image. The aim of this study was to evaluate the clinical and microbiological effect of antimicrobial photodynamic therapy (aPDT) on halitosis in adolescents. Forty-six individuals aged 12 to 19 years were randomly allocated: Group 1 – treatment with photodynamic therapy; Group 2 – treatment with a tongue scraper and Group 3 – treatment with a tongue scraper and photodynamic therapy. The count of bacterial colony-forming units per milliliter was used for the microbiological analysis. Statistical analysis involved the Kruskal–Wallis test followed by the Student–Newman–Keuls test. ANOVA was used for the determination of colony-forming units after treatment. The level of significance for all statistical tests was 5% (p < 0.05). After treatment, a statistically significant reduction in total volatile sulfur compounds was found in all groups (p < 0.001), with the largest reduction (median: 0) found in Group 3 (tongue scraper and photodynamic therapy). Moreover, a statistically significant difference was found between treatment with aPDT and a tongue scraper alone (p < 0.001). The present findings demonstrate an option for the treatment of halitosis in adolescents, with an immediate effect and without the mechanical aggression to the toungue. (Figure presented.) Clinical Trials: NCT02007993.
KW - Halitosis
KW - adolescent
KW - laser
KW - photodynamic therapy
KW - tongue
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U2 - 10.1002/jbio.201600067
DO - 10.1002/jbio.201600067
M3 - Article
C2 - 27248838
AN - SCOPUS:84973109429
SN - 1864-063X
VL - 9
SP - 1337
EP - 1343
JO - Journal of Biophotonics
JF - Journal of Biophotonics
IS - 11-12
ER -