Abstract
Endocannabinoids are generally known to suppress excitatory or inhibitory synaptic transmission. Now, in an elegant series of experiments, Cachope et al. reveal a novel signaling pathway whereby endocannabinoids indirectly potentiate mixed chemical and electrical synapses. Gap junction-mediated transmission can thus be potentiated via distinct frequency-dependent mechanisms.
Original language | English (US) |
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Pages (from-to) | 945-946 |
Number of pages | 2 |
Journal | Neuron |
Volume | 56 |
Issue number | 6 |
DOIs | |
State | Published - Dec 20 2007 |
ASJC Scopus subject areas
- General Neuroscience