Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

George R. Wandling, Mansi Parikh, Christopher Robinson, Sudeep N. Pramanik, Kenneth M. Goins, John E. Sutphin, Wallace L.M. Alward, Emily C. Greenlee, Young H. Kwon, Michael D. Wagoner

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Purpose: To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Methods: Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Results: Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Conclusion: Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.

Original languageEnglish (US)
Pages (from-to)991-995
Number of pages5
Issue number9
StatePublished - Sep 2010
Externally publishedYes


  • deep lamellar endothelial keratoplasty
  • endothelial keratoplasty
  • glaucoma
  • graft failure

ASJC Scopus subject areas

  • Ophthalmology


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