Extracorporeal membrane oxygenation for profound cardiogenic shock due to cocaine toxicity

Joshua C. Grimm, Keki R. Balsara, Clinton D. Kemp, Jared Miller, Mollie Myers, Steven P. Schulman, Christopher M. Sciortino

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Cocaine toxicity can result in myocardial infarction from coronary vasospasm. The current treatment algorithm includes intravenous and/or intracoronary vasodilator administration with an expectantly quick resolution of symptoms and signs of ischemia. However, in situations in which myocardial injury persists, the optimal management is uncertain. We present a case in which extracorporeal membrane oxygenation effectively stabilized a patient with ongoing hemodynamic instability who experienced repeated episodes of myocardial injury and ventricular tachyarrhythmias due to cocaine toxicity.<. Learning objective: In many urban settings, cocaine-induced angina is not uncommon. The pathogenesis of its manifestation includes coronary artery vasospasm and decreased left ventricular function. Treatment typically involves systemic vasodilators, such as nitrates and calcium channel blockers. However, in patients with substantial hemodynamic instability, these agents might result in a worsening of systemic perfusion. Accordingly, extracorporeal membrane oxygenation should be considered in such cases to promote myocardial recovery.>.

Original languageEnglish (US)
Pages (from-to)28-31
Number of pages4
JournalJournal of Cardiology Cases
Issue number1
StatePublished - Jan 1 2015
Externally publishedYes


  • Cocaine toxicity
  • Coronary artery vasospasm
  • Extracorporeal membrane oxygenation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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