TY - JOUR
T1 - Features of amiodarone-induced optic neuropathy
AU - MacAluso, Damien C.
AU - Shults, William T.
AU - Fraunfelder, Frederick T.
PY - 1999/5
Y1 - 1999/5
N2 - PURPOSE: To report clinical features of amiodarone-induced optic neuropathy and outline the differentiation of amiodarone optic neuropathy from nonarteritic anterior ischemic optic neuropathy. METHOD: We reviewed data from 73 patients reported to have developed an optic neuropathy while taking amiodarone. RESULTS: Amiodarone optic neuropathy is characterized by an insidious onset, slow progression, bilateral visual loss, and protracted disk swelling that tends to stabilize within several months of discontinuing the medication. Nonarteritic ischemic optic neuropathy is characterized by acute, unilateral visual loss that is usually complete at onset, with resolution of disk edema over several weeks. CONCLUSION. Unique clinical features of amiodarone-induced optic neuropathy may help clinicians diagnose and distinguish between amiodarone-induced optic neuropathy and nonarteritic anterior ischemic optic neuropathy.
AB - PURPOSE: To report clinical features of amiodarone-induced optic neuropathy and outline the differentiation of amiodarone optic neuropathy from nonarteritic anterior ischemic optic neuropathy. METHOD: We reviewed data from 73 patients reported to have developed an optic neuropathy while taking amiodarone. RESULTS: Amiodarone optic neuropathy is characterized by an insidious onset, slow progression, bilateral visual loss, and protracted disk swelling that tends to stabilize within several months of discontinuing the medication. Nonarteritic ischemic optic neuropathy is characterized by acute, unilateral visual loss that is usually complete at onset, with resolution of disk edema over several weeks. CONCLUSION. Unique clinical features of amiodarone-induced optic neuropathy may help clinicians diagnose and distinguish between amiodarone-induced optic neuropathy and nonarteritic anterior ischemic optic neuropathy.
UR - http://www.scopus.com/inward/record.url?scp=0032962579&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032962579&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(99)00016-1
DO - 10.1016/S0002-9394(99)00016-1
M3 - Article
C2 - 10334361
AN - SCOPUS:0032962579
SN - 0002-9394
VL - 127
SP - 610
EP - 612
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 5
ER -