Fluocinolone acetonide intravitreal implants in vogt-koyanagi-harada disease

Yousuf Khalifa; Allison R. Loh; Nisha R. Acharya

doi:10.3109/09273940903267936

Fluocinolone acetonide intravitreal implants in vogt-koyanagi-harada disease

Yousuf Khalifa, Allison R. Loh, Nisha R. Acharya

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Purpose: To describe the use of fluocinolone acetonide implants (Retisert) in Vogt-Koyanagi-Harada disease (VKH). Design: Interventional case series. Methods: Retrospective review of medical records. Results: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned. Conclusions: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.

Original language	English (US)
Pages (from-to)	431-433
Number of pages	3
Journal	Ocular Immunology and Inflammation
Volume	17
Issue number	6
DOIs	https://doi.org/10.3109/09273940903267936
State	Published - Dec 2009
Externally published	Yes

Keywords

Fluocinolone acetonide intravitreal implant
Uveitis
Vogt-Koyanagi-Harada

ASJC Scopus subject areas

Immunology and Allergy
Ophthalmology

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10.3109/09273940903267936

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title = "Fluocinolone acetonide intravitreal implants in vogt-koyanagi-harada disease",

abstract = "Purpose: To describe the use of fluocinolone acetonide implants (Retisert) in Vogt-Koyanagi-Harada disease (VKH). Design: Interventional case series. Methods: Retrospective review of medical records. Results: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned. Conclusions: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.",

keywords = "Fluocinolone acetonide intravitreal implant, Uveitis, Vogt-Koyanagi-Harada",

author = "Yousuf Khalifa and Loh, {Allison R.} and Acharya, {Nisha R.}",

note = "Funding Information: The Department of Ophthalmology at UCSF is supported by a core grant from the National Eye Institute, EY02162. Dr. Acharya is supported by a National Eye Institute K23EY017897 grant and a Research to Prevent Blindness Career Development Award. This work was supported in part by a grant from the Doris Duke Charitable Foundation to UCSF to fund Allison Loh.",

year = "2009",

month = dec,

doi = "10.3109/09273940903267936",

language = "English (US)",

volume = "17",

pages = "431--433",

journal = "Ocular Immunology and Inflammation",

issn = "0927-3948",

publisher = "Taylor and Francis Ltd.",

number = "6",

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T1 - Fluocinolone acetonide intravitreal implants in vogt-koyanagi-harada disease

AU - Khalifa, Yousuf

AU - Loh, Allison R.

AU - Acharya, Nisha R.

N1 - Funding Information: The Department of Ophthalmology at UCSF is supported by a core grant from the National Eye Institute, EY02162. Dr. Acharya is supported by a National Eye Institute K23EY017897 grant and a Research to Prevent Blindness Career Development Award. This work was supported in part by a grant from the Doris Duke Charitable Foundation to UCSF to fund Allison Loh.

PY - 2009/12

Y1 - 2009/12

N2 - Purpose: To describe the use of fluocinolone acetonide implants (Retisert) in Vogt-Koyanagi-Harada disease (VKH). Design: Interventional case series. Methods: Retrospective review of medical records. Results: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned. Conclusions: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.

AB - Purpose: To describe the use of fluocinolone acetonide implants (Retisert) in Vogt-Koyanagi-Harada disease (VKH). Design: Interventional case series. Methods: Retrospective review of medical records. Results: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned. Conclusions: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.

KW - Fluocinolone acetonide intravitreal implant

KW - Uveitis

KW - Vogt-Koyanagi-Harada

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Fluocinolone acetonide intravitreal implants in vogt-koyanagi-harada disease

Abstract

Keywords

ASJC Scopus subject areas

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