Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array

Amin Nikoozadeh; Ömer Oralkan; Mustafa Gencel; Jung Woo Choe; Douglas N. Stephens; Alan De La Rama; Peter Chen; Kai Thomenius; Aaron Dentinger; Douglas Wildes; Kalyanam Shivkumar; Aman Mahajan; Matthew O'Donnell; David Sahn; Pierre T. Khuri-Yakub

doi:10.1109/ULTSYM.2009.5441600

Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array

Amin Nikoozadeh, Ömer Oralkan, Mustafa Gencel, Jung Woo Choe, Douglas N. Stephens, Alan De La Rama, Peter Chen, Kai Thomenius, Aaron Dentinger, Douglas Wildes, Kalyanam Shivkumar, Aman Mahajan, Matthew O'Donnell, David Sahn, Pierre T. Khuri-Yakub

Pediatrics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

41 Scopus citations

Abstract

Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.

Original language	English (US)
Title of host publication	2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	511-514
Number of pages	4
ISBN (Print)	9781424443895
DOIs	https://doi.org/10.1109/ULTSYM.2009.5441600
State	Published - 2009
Event	2009 IEEE International Ultrasonics Symposium, IUS 2009 - Rome, Italy Duration: Sep 20 2009 → Sep 23 2009

Publication series

Name	Proceedings - IEEE Ultrasonics Symposium
ISSN (Print)	1051-0117

Other

Other	2009 IEEE International Ultrasonics Symposium, IUS 2009
Country/Territory	Italy
City	Rome
Period	9/20/09 → 9/23/09

Keywords

CMUT
Capacitive micromachined ultrasonic transducers
Electrophysiology
Forward-looking
Intracardiac echo
Real-time
Ultrasound
Volumetric

ASJC Scopus subject areas

Acoustics and Ultrasonics

Access to Document

10.1109/ULTSYM.2009.5441600

Cite this

Nikoozadeh, A., Oralkan, Ö., Gencel, M., Choe, J. W., Stephens, D. N., De La Rama, A., Chen, P., Thomenius, K., Dentinger, A., Wildes, D., Shivkumar, K., Mahajan, A., O'Donnell, M., Sahn, D., & Khuri-Yakub, P. T. (2009). Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array. In 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009 (pp. 511-514). Article 5441600 (Proceedings - IEEE Ultrasonics Symposium). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ULTSYM.2009.5441600

Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array. / Nikoozadeh, Amin; Oralkan, Ömer; Gencel, Mustafa et al.
2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. Institute of Electrical and Electronics Engineers Inc., 2009. p. 511-514 5441600 (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nikoozadeh, A, Oralkan, Ö, Gencel, M, Choe, JW, Stephens, DN, De La Rama, A, Chen, P, Thomenius, K, Dentinger, A, Wildes, D, Shivkumar, K, Mahajan, A, O'Donnell, M, Sahn, D & Khuri-Yakub, PT 2009, Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array. in 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009., 5441600, Proceedings - IEEE Ultrasonics Symposium, Institute of Electrical and Electronics Engineers Inc., pp. 511-514, 2009 IEEE International Ultrasonics Symposium, IUS 2009, Rome, Italy, 9/20/09. https://doi.org/10.1109/ULTSYM.2009.5441600

Nikoozadeh A, Oralkan Ö, Gencel M, Choe JW, Stephens DN, De La Rama A et al. Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array. In 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. Institute of Electrical and Electronics Engineers Inc. 2009. p. 511-514. 5441600. (Proceedings - IEEE Ultrasonics Symposium). doi: 10.1109/ULTSYM.2009.5441600

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abstract = "Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.",

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AU - Nikoozadeh, Amin

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AU - Gencel, Mustafa

AU - Choe, Jung Woo

AU - Stephens, Douglas N.

AU - De La Rama, Alan

AU - Chen, Peter

AU - Thomenius, Kai

AU - Dentinger, Aaron

AU - Wildes, Douglas

AU - Shivkumar, Kalyanam

AU - Mahajan, Aman

AU - O'Donnell, Matthew

AU - Sahn, David

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N2 - Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.

AB - Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.

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KW - Capacitive micromachined ultrasonic transducers

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ER -

Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array

Abstract

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Keywords

ASJC Scopus subject areas

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