Gingival plasma cell granuloma

Mark E. Peacock, Steven D. Hokett, John W. Hellstein, Robert W. Herold, Scott A. Matzenbacher, Donald K. Scales, Michael F. Cuenin

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.

Original languageEnglish (US)
Pages (from-to)1287-1290
Number of pages4
JournalJournal of periodontology
Issue number9
StatePublished - Sep 2001
Externally publishedYes


  • Gingival hyperplasia/diagnosis
  • Gingival neoplasms/diagnosis
  • Granuloma
  • Plasma cell

ASJC Scopus subject areas

  • Periodontics


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