Granular Cell Tumor in the Ascending Colon

Takahiro Yamada, Eizaburo Sasatomi, Shigeo Nakano, Osamu Tokunaga, Takahiro Yamada, Yu Fujiwara

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We describe a case of multiple polypoid lesions that occurred in the colon of a 62-year-old man. Eight of the lesions were demonstrated by barium enema, and five were examined histologically. A small nodule in the submucosa of the ascending colon was histologically identical to granular cell tumor, characterized by nested growth of large tumor cells with ample granular cytoplasm and small round nuclei. Immunohistochemically, the cells were positive for S-100, neuron-specific enolase and vimentin, and negative for α-smooth muscle actin and desmin.

Original languageEnglish (US)
Pages (from-to)657-660
Number of pages4
JournalInternal Medicine
Issue number7
StatePublished - 1995
Externally publishedYes


  • S-100
  • desmin
  • neuron-specific enolase
  • α-smooth muscle actin

ASJC Scopus subject areas

  • Internal Medicine


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