Hairy cell leukemia

Ronan Swords, Francis Giles

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with "hairy" lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.

Original languageEnglish (US)
Pages (from-to)7-15
Number of pages9
JournalMedical Oncology
Issue number1
StatePublished - Jun 2007
Externally publishedYes


  • Hairy cell leukemia
  • Pathophysiology
  • Purine analogs
  • Treatment

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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