Hairy cell leukemia

Ronan Swords; Francis Giles

doi:10.1007/BF02685898

Hairy cell leukemia

Ronan Swords, Francis Giles

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with "hairy" lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.

Original language	English (US)
Pages (from-to)	7-15
Number of pages	9
Journal	Medical Oncology
Volume	24
Issue number	1
DOIs	https://doi.org/10.1007/BF02685898
State	Published - Jun 2007
Externally published	Yes

Keywords

Hairy cell leukemia
Pathophysiology
Purine analogs
Treatment

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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10.1007/BF02685898

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AU - Giles, Francis

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AB - Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with "hairy" lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.

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KW - Pathophysiology

KW - Purine analogs

KW - Treatment

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Hairy cell leukemia

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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