Health-related quality of life for children with ASD: Associations with behavioral characteristics

Karen Kuhlthau, Erica Kovacs, Trevor Hall, Traci Clemmons, Felice Orlich, Jennifer Delahaye, Darryn Sikora

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


This paper examines health-related quality of life (HRQoL) of children age 6-11 years with an autism spectrum disorder (ASD) using the Child Health and Illness Profile - Child Edition (CHIP-CE). We further examine associations of HRQoL scores with measures of behavior using regression models. Overall HRQoL scores are lower than those for normative samples. We find that both externalizing and internalizing behaviors (measured with the Child Behavior Checklist) are correlated with HRQoL as are several of the subscales of the aberrant behavior checklist. These results suggest that some potentially modifiable aspects of ASD, in particular ASD-related and aberrant behaviors, are associated with HRQoL. These associations are suggestive of the potential for improvements in behaviors in some domains having the potential to improve HRQoL. Future studies should determine whether improvements in behaviors are associated with improvements in HRQoL.

Original languageEnglish (US)
Pages (from-to)1035-1042
Number of pages8
JournalResearch in Autism Spectrum Disorders
Issue number9
StatePublished - 2013
Externally publishedYes


  • Behavior
  • Health-related quality of life

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Clinical Psychology
  • Psychiatry and Mental health


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