Heart Failure in Adult Congenital Heart Disease. Nonpharmacologic Treatment Strategies.

Lisa LeMond, Tuan Mai, Craig S. Broberg, Ashok Muralidaran, Luke J. Burchill

    Research output: Contribution to journalReview articlepeer-review

    5 Scopus citations


    In early stages, heart failure (HF) in adult congenital heart disease (ACHD) remains an elusive diagnosis. Many ACHD patients seem well-compensated owing to chronic physical and psychological adaptations. HF biomarkers and cardiopulmonary exercise tests are often markedly abnormal, although patients report stable health and good quality of life. Treatment differs from acquired HF. Evidence for effective drug therapy in ACHD-related HF is lacking. Residual ventricular, valvular, and vascular abnormalities contribute to HF pathophysiology, leading to an emphasis on nonpharmacologic treatment strategies. This article reviews emerging perspectives on nonpharmacologic treatment strategies, including catheter-based interventions, surgical correction, and palliative care.

    Original languageEnglish (US)
    Pages (from-to)589-598
    Number of pages10
    JournalCardiology Clinics
    Issue number4
    StatePublished - Nov 2015


    • Adult congenital heart disease
    • Arrhythmia
    • Biomarkers
    • Cardiac surgery
    • Heart failure
    • Structural intervention

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine


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