Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis

the HRC neurodevelopmental follow-up investigators

doi:10.1016/j.earlhumdev.2021.105419

Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis

the HRC neurodevelopmental follow-up investigators

Pediatrics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18–22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment.

Original language	English (US)
Article number	105419
Journal	Early Human Development
Volume	159
DOIs	https://doi.org/10.1016/j.earlhumdev.2021.105419
State	Published - Aug 2021

Keywords

Extremely low birth weight, ELBW
Heart rate characteristics, HRC
Heart rate variability, HRV
Infant
Infant health
Infant, extremely low birth weight
Infant, extremely premature
Late onset sepsis, LOS
NICU
Neurodevelopmental impairment, NDI
Newborn infant
Randomized controlled trial, RCT

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1016/j.earlhumdev.2021.105419

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@article{51d22f0a884246e19c8dc872cab72fb6,

title = "Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis",

abstract = "We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18–22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment.",

keywords = "Extremely low birth weight, ELBW, Heart rate characteristics, HRC, Heart rate variability, HRV, Infant, Infant health, Infant, extremely low birth weight, Infant, extremely premature, Late onset sepsis, LOS, NICU, Neurodevelopmental impairment, NDI, Newborn infant, Randomized controlled trial, RCT",

author = "{the HRC neurodevelopmental follow-up investigators} and King, {William E.} and Carlo, {Waldemar A.} and O'Shea, {T. Michael} and Schelonka, {Robert L.}",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

month = aug,

doi = "10.1016/j.earlhumdev.2021.105419",

language = "English (US)",

volume = "159",

journal = "Early Human Development",

issn = "0378-3782",

publisher = "Elsevier Ireland Ltd",

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T1 - Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis

AU - the HRC neurodevelopmental follow-up investigators

AU - King, William E.

AU - Carlo, Waldemar A.

AU - O'Shea, T. Michael

AU - Schelonka, Robert L.

PY - 2021/8

Y1 - 2021/8

N2 - We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18–22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment.

AB - We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18–22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment.

KW - Extremely low birth weight, ELBW

KW - Heart rate characteristics, HRC

KW - Heart rate variability, HRV

KW - Infant

KW - Infant health

KW - Infant, extremely low birth weight

KW - Infant, extremely premature

KW - Late onset sepsis, LOS

KW - NICU

KW - Neurodevelopmental impairment, NDI

KW - Newborn infant

KW - Randomized controlled trial, RCT

UR - http://www.scopus.com/inward/record.url?scp=85109440540&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85109440540&partnerID=8YFLogxK

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DO - 10.1016/j.earlhumdev.2021.105419

M3 - Article

C2 - 34247026

AN - SCOPUS:85109440540

SN - 0378-3782

VL - 159

JO - Early Human Development

JF - Early Human Development

M1 - 105419

ER -

Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis

Abstract

Keywords

ASJC Scopus subject areas

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