Hemorrhagic vestibular schwannoma: Review of the literature

Yashar S. Niknafs, Anthony C. Wang, Khoi D. Than, Arnold B. Etame, B. Gregory Thompson, Stephen E. Sullivan

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


Background Clinically significant intratumoral hemorrhage historically has been reported in only a small fraction of vestibular schwannomas (VS). Patients with hemorrhagic VS are more likely to present with neurologic deficits and have worse outcomes than patients with nonhemorrhagic VS.

Methods A literature search was conducted using National Library of Medicine and National Institutes of Health databases to identify articles pertaining to intratumoral hemorrhage in VS. The authors selected 39 cases, described in 18 published articles, to review.

Results Average patient age and tumor size in hemorrhagic cases of VS did not differ significantly from nonhemorrhagic cases of VS. Facial nerve dysfunction at presentation occurred with greater frequency in cases of hemorrhagic VS (33.3%) than in nonhemorrhagic VS (6.0%). Death occurred much more frequently in cases of hemorrhagic VS (10.0%) than in nonhemorrhagic VS (0.2%). Abnormality of tumor-associated vasculature was noted histologically in many cases, and a large number of the cases reported prior treatment by stereotactic radiosurgery.

Conclusions Understanding the origins and clinical implications of intratumoral hemorrhage in VS could potentially assist in clinical decision making and patient counseling.

Original languageEnglish (US)
Pages (from-to)751-756
Number of pages6
JournalWorld Neurosurgery
Issue number5
StatePublished - Nov 1 2014
Externally publishedYes


  • Acoustic neuroma
  • Intratumoral hemorrhage
  • Vestibular schwannoma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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