Host-range control of a retroviral disease: Friend erythroleukemia

M. E. Hoatlin; D. Kabat

doi:10.1016/S0966-842X(00)88875-7

Host-range control of a retroviral disease: Friend erythroleukemia

M. E. Hoatlin, D. Kabat

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Abstract

Since its discovery in 1957, Friend viral erythroleukemia has been the major model for understanding host genetic barriers to retroviral diseases and has facilitated the discovery of many polymorphic leukemia-control genes of mice. Some of these genes limit helper-virus replication, target-cell (erythroblast) pools or immune responses. At least one host gene appears to block the viral oncoprotein.

Original language	English (US)
Pages (from-to)	51-57
Number of pages	7
Journal	Trends in microbiology
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/S0966-842X(00)88875-7
State	Published - Feb 1995
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

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10.1016/S0966-842X(00)88875-7

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title = "Host-range control of a retroviral disease: Friend erythroleukemia",

abstract = "Since its discovery in 1957, Friend viral erythroleukemia has been the major model for understanding host genetic barriers to retroviral diseases and has facilitated the discovery of many polymorphic leukemia-control genes of mice. Some of these genes limit helper-virus replication, target-cell (erythroblast) pools or immune responses. At least one host gene appears to block the viral oncoprotein.",

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AB - Since its discovery in 1957, Friend viral erythroleukemia has been the major model for understanding host genetic barriers to retroviral diseases and has facilitated the discovery of many polymorphic leukemia-control genes of mice. Some of these genes limit helper-virus replication, target-cell (erythroblast) pools or immune responses. At least one host gene appears to block the viral oncoprotein.

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Host-range control of a retroviral disease: Friend erythroleukemia

Abstract

ASJC Scopus subject areas

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