How long is too long: Does a prolonged second stage of labor in nulliparous women affect maternal and neonatal outcomes?

Yvonne W. Cheng, Linda M. Hopkins, Aaron B. Caughey

Research output: Contribution to journalArticlepeer-review

221 Scopus citations


The purpose of this study was to examine maternal and neonatal outcomes in relation to lengthening intervals of the second stage of labor. This is a retrospective cohort study of 15,759 nulliparous, term, cephalic, singleton births at the University of California, San Francisco, between 1976 and 2001. The second stage of labor was divided into 1-hour intervals. Maternal and neonatal outcomes were compared with the use of chi-squared and Student t tests, and a probability value of ≤.05 was used to indicate statistical significance. Potential confounders were controlled for with multivariate logistic regression. Increasing rates of cesarean delivery, operative vaginal delivery, and perineal trauma were associated with the second stage beyond the first hour. In multivariate analysis, the >4-hour interval group had higher rates of cesarean delivery (odds ratio, 5.65; P <. 001), operative vaginal deliveries (odds ratio, 2.83; P <. 001), 3rd- or 4th-degree perineal lacerations (odds ratio, 1.33; P =. 009), and chorioamnionitis (odds ratio, 1.79; P <. 001). There were no differences in neonatal acid-base status associated with length of second stage. However, there were fewer neonates with a 5-minute Apgar score of <7 (odds ratio, 0.45; P =. 01). Although the length of the second stage of labor is not associated with poor neonatal outcome, a prolonged second stage is associated with increased maternal morbidity and operative delivery rates.

Original languageEnglish (US)
Pages (from-to)933-938
Number of pages6
JournalAmerican journal of obstetrics and gynecology
Issue number3
StatePublished - Sep 2004
Externally publishedYes


  • Complication
  • Mode of delivery
  • Second stage of labor

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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