Human fibroblast interferon gene lacks introns

Richard M. Lawn, John Adelman, Arthur E. Franke, Catherine M. Houck, Mitchell Gross, Richard Najarian, David V. Goeddel

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


A recombinant λ bacteriophage isolated from a human genome library contains the gene for fibroblast interferon (IFN-β1). The DNA sequence of this gene is identical to the sequence of its mRNA and is devoid of introns.

Original languageEnglish (US)
Pages (from-to)1045-1052
Number of pages8
JournalNucleic acids research
Issue number5
StatePublished - Jan 1 1981
Externally publishedYes

ASJC Scopus subject areas

  • Genetics


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