Hypothalamic epinephrine is released into hypophysial portal blood during stress

Daniel M. Gibbs

doi:10.1016/0006-8993(85)90494-9

Hypothalamic epinephrine is released into hypophysial portal blood during stress

Daniel M. Gibbs

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The hypothalamic secretion of epinephrine (EPI), norepinephrine (NE), and dopamine (DA) into hypophysial portal blood was studied in adrenalectomized rats subjected to heat stress. Portal plasma EPI levels were increased 3-fold by heat stress whereas portal plasma concentrations of NE and DA were not altered by stress. These data suggest that EPI of hypothalamic origin may be involved directly in the modulation of anterior pituitary secretion during stress.

Original language	English (US)
Pages (from-to)	360-364
Number of pages	5
Journal	Brain research
Volume	335
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(85)90494-9
State	Published - Jun 3 1985
Externally published	Yes

Keywords

dopamine
epinephrine
hypophysial portal blood
norepinephrine
stress

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(85)90494-9

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title = "Hypothalamic epinephrine is released into hypophysial portal blood during stress",

abstract = "The hypothalamic secretion of epinephrine (EPI), norepinephrine (NE), and dopamine (DA) into hypophysial portal blood was studied in adrenalectomized rats subjected to heat stress. Portal plasma EPI levels were increased 3-fold by heat stress whereas portal plasma concentrations of NE and DA were not altered by stress. These data suggest that EPI of hypothalamic origin may be involved directly in the modulation of anterior pituitary secretion during stress.",

keywords = "dopamine, epinephrine, hypophysial portal blood, norepinephrine, stress",

author = "Gibbs, {Daniel M.}",

note = "Funding Information: This study was supported in part by a Mellon Foundation Faculty Scholar Award and by NIH Grant AM-32517. I would like to thank S. Simerson for skillful technical assistance.",

year = "1985",

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doi = "10.1016/0006-8993(85)90494-9",

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AU - Gibbs, Daniel M.

N1 - Funding Information: This study was supported in part by a Mellon Foundation Faculty Scholar Award and by NIH Grant AM-32517. I would like to thank S. Simerson for skillful technical assistance.

PY - 1985/6/3

Y1 - 1985/6/3

N2 - The hypothalamic secretion of epinephrine (EPI), norepinephrine (NE), and dopamine (DA) into hypophysial portal blood was studied in adrenalectomized rats subjected to heat stress. Portal plasma EPI levels were increased 3-fold by heat stress whereas portal plasma concentrations of NE and DA were not altered by stress. These data suggest that EPI of hypothalamic origin may be involved directly in the modulation of anterior pituitary secretion during stress.

AB - The hypothalamic secretion of epinephrine (EPI), norepinephrine (NE), and dopamine (DA) into hypophysial portal blood was studied in adrenalectomized rats subjected to heat stress. Portal plasma EPI levels were increased 3-fold by heat stress whereas portal plasma concentrations of NE and DA were not altered by stress. These data suggest that EPI of hypothalamic origin may be involved directly in the modulation of anterior pituitary secretion during stress.

KW - dopamine

KW - epinephrine

KW - hypophysial portal blood

KW - norepinephrine

KW - stress

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AN - SCOPUS:0021880839

SN - 0006-8993

VL - 335

SP - 360

EP - 364

JO - Brain research

JF - Brain research

IS - 2

ER -

Hypothalamic epinephrine is released into hypophysial portal blood during stress

Abstract

Keywords

ASJC Scopus subject areas

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