Hypothalamic epinephrine is released into hypophysial portal blood during stress

Daniel M. Gibbs

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


The hypothalamic secretion of epinephrine (EPI), norepinephrine (NE), and dopamine (DA) into hypophysial portal blood was studied in adrenalectomized rats subjected to heat stress. Portal plasma EPI levels were increased 3-fold by heat stress whereas portal plasma concentrations of NE and DA were not altered by stress. These data suggest that EPI of hypothalamic origin may be involved directly in the modulation of anterior pituitary secretion during stress.

Original languageEnglish (US)
Pages (from-to)360-364
Number of pages5
JournalBrain research
Issue number2
StatePublished - Jun 3 1985
Externally publishedYes


  • dopamine
  • epinephrine
  • hypophysial portal blood
  • norepinephrine
  • stress

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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