TY - JOUR
T1 - Identifying a Relationship between Physical Frailty and Heart Failure Symptoms
AU - Denfeld, Quin E.
AU - Winters-Stone, Kerri
AU - Mudd, James O.
AU - Hiatt, Shirin O.
AU - Lee, Christopher S.
N1 - Publisher Copyright:
Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background: Heart failure (HF) is a complex clinical syndrome associated with significant symptom burden; however, our understanding of the relationship between symptoms and physical frailty in HF is limited. Objective: The aim of this study was to quantify associations between symptoms and physical frailty in adults with HF. Methods: A sample of adults with symptomatic HF were enrolled in a cross-sectional study. Physical symptoms were measured with the HF Somatic Perception Scale-Dyspnea subscale, the Epworth Sleepiness Scale, and the Brief Pain Inventory short form. Affective symptoms were measured with the Patient Health Questionnaire-9 and the Brief Symptom Inventory-Anxiety scale. Physical frailty was assessed according to the Frailty Phenotype Criteria: shrinking, weakness, slowness, physical exhaustion, and low physical activity. Comparative statistics and generalized linear modeling were used to quantify associations between symptoms and physical frailty, controlling for Seattle HF Model projected 1-year survival. Results: The mean age of the sample (n = 49) was 57.4 ± 9.7 years, 67% were male, 92% had New York Heart Association class III/IV HF, and 67% had nonischemic HF. Physically frail participants had more than twice the level of dyspnea (P <.001), 75% worse wake disturbances (P <.001), and 76% worse depressive symptoms (P =.003) compared with those who were not physically frail. There were no differences in pain or anxiety. Conclusions: Physically frail adults with HF have considerably worse dyspnea, wake disturbances, and depression. Targeting physical frailty may help identify and improve physical and affective symptoms in HF.
AB - Background: Heart failure (HF) is a complex clinical syndrome associated with significant symptom burden; however, our understanding of the relationship between symptoms and physical frailty in HF is limited. Objective: The aim of this study was to quantify associations between symptoms and physical frailty in adults with HF. Methods: A sample of adults with symptomatic HF were enrolled in a cross-sectional study. Physical symptoms were measured with the HF Somatic Perception Scale-Dyspnea subscale, the Epworth Sleepiness Scale, and the Brief Pain Inventory short form. Affective symptoms were measured with the Patient Health Questionnaire-9 and the Brief Symptom Inventory-Anxiety scale. Physical frailty was assessed according to the Frailty Phenotype Criteria: shrinking, weakness, slowness, physical exhaustion, and low physical activity. Comparative statistics and generalized linear modeling were used to quantify associations between symptoms and physical frailty, controlling for Seattle HF Model projected 1-year survival. Results: The mean age of the sample (n = 49) was 57.4 ± 9.7 years, 67% were male, 92% had New York Heart Association class III/IV HF, and 67% had nonischemic HF. Physically frail participants had more than twice the level of dyspnea (P <.001), 75% worse wake disturbances (P <.001), and 76% worse depressive symptoms (P =.003) compared with those who were not physically frail. There were no differences in pain or anxiety. Conclusions: Physically frail adults with HF have considerably worse dyspnea, wake disturbances, and depression. Targeting physical frailty may help identify and improve physical and affective symptoms in HF.
KW - heart failure
KW - physical frailty
KW - symptoms
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U2 - 10.1097/JCN.0000000000000408
DO - 10.1097/JCN.0000000000000408
M3 - Article
C2 - 28353543
AN - SCOPUS:85016400945
SN - 0889-4655
VL - 33
SP - E1-E7
JO - Journal of Cardiovascular Nursing
JF - Journal of Cardiovascular Nursing
IS - 1
ER -