Imaging serpiginous choroidopathy with spectral domain optical coherence tomography

Omar S. Punjabi, Ryan Rich, Janet L. Davis, Giovanni Gregori, Harry W. Flynn, Brandon J. Lujan, Philip J. Rosenfeld, Carmen A. Puliafito

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The use of spectral domain optical coherence tomography (SD-OCT) in the study of chronic serpiginous choroiditis was evaluated. Two patients with chronic serpiginous choroiditis were imaged using two prototype SD-OCT systems (6-μm axial resolution). Raster scans covering 6 × 6 × 2-mm regions of the retina were obtained, enabling the study of different retinal cross-sectional images. Thickness maps were obtained after segmentation of retinal layers, which could be compared with those on follow-up. SD-OCT allowed the visualization of the cross-sectional retinal architecture at different horizontal positions. Superimposition of SD-OCT generated reconstructed fundus images with fundus photographs provided accurate images registration. Segmentation of retinal layers provided thickness maps and higher-density improved visualization of photoreceptor layer, cysts, and atrophy, which was useful in following change in disease activity over time. The researchers concluded that SD-OCT is a useful tool to study disease morphology and follow-up of chronic serpiginous choroiditis.

Original languageEnglish (US)
Pages (from-to)S95-S98
JournalOphthalmic Surgery Lasers and Imaging
Issue number4 SUPPL.
StatePublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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