TY - JOUR
T1 - Immediate results of photodynamic therapy for the treatment of halitosis in adolescents
T2 - a randomized, controlled, clinical trial
AU - Lopes, Rubia Garcia
AU - da Mota, Ana Carolina Costa
AU - Soares, Carolina
AU - Tarzia, Olinda
AU - Deana, Alessandro Melo
AU - Prates, Renato Araújo
AU - França, Cristiane Miranda
AU - Fernandes, Kristianne Porta Santos
AU - Ferrari, Raquel Agnelli Mesquita
AU - Bussadori, Sandra Kalil
N1 - Publisher Copyright:
© 2015, Springer-Verlag London.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Light with or without chemical agents has been used to induce therapeutic and antimicrobial effects. With photodynamic therapy, the antimicrobial effect is confined to areas covered by a photosensitive dye and irradiated with light. The aim of the present study was to evaluate the effect of photodynamic therapy for the treatment of halitosis in adolescents through the analysis of volatile sulfur compounds, especially sulfide. A controlled, clinical trial was conducted with 45 adolescents randomly allocated to three groups: group 1, photodynamic therapy administered to the dorsum of the tongue; group 2, treatment with a tongue scraper; and group 3, treatment with a tongue scraper combined with photodynamic therapy. The diagnosis of halitosis was performed using gas chromatography before and after treatment. Comparisons were made using the Kruskal-Wallis test followed by the Student-Newman-Keuls test, with the level of significance set at 5 % (p < 0.05). After treatment, a statistically significant reduction in halitosis was found in all groups (p < 0.001). The greatest reduction in total sulfides (median = 0) occurred with the combination of tongue scraper and photodynamic therapy. The present study describes a novel option for the treatment of halitosis in adolescents with an immediate effect that does not involve the mechanical aggression of the lingual papillae that occurs with conventional treatment. Trial registration: Photodynamic Therapy in Adolescents Halitosis (https://clinicaltrials.gov/ct2/show/NCT02007993?term=NCT02007993&rank=1)
AB - Light with or without chemical agents has been used to induce therapeutic and antimicrobial effects. With photodynamic therapy, the antimicrobial effect is confined to areas covered by a photosensitive dye and irradiated with light. The aim of the present study was to evaluate the effect of photodynamic therapy for the treatment of halitosis in adolescents through the analysis of volatile sulfur compounds, especially sulfide. A controlled, clinical trial was conducted with 45 adolescents randomly allocated to three groups: group 1, photodynamic therapy administered to the dorsum of the tongue; group 2, treatment with a tongue scraper; and group 3, treatment with a tongue scraper combined with photodynamic therapy. The diagnosis of halitosis was performed using gas chromatography before and after treatment. Comparisons were made using the Kruskal-Wallis test followed by the Student-Newman-Keuls test, with the level of significance set at 5 % (p < 0.05). After treatment, a statistically significant reduction in halitosis was found in all groups (p < 0.001). The greatest reduction in total sulfides (median = 0) occurred with the combination of tongue scraper and photodynamic therapy. The present study describes a novel option for the treatment of halitosis in adolescents with an immediate effect that does not involve the mechanical aggression of the lingual papillae that occurs with conventional treatment. Trial registration: Photodynamic Therapy in Adolescents Halitosis (https://clinicaltrials.gov/ct2/show/NCT02007993?term=NCT02007993&rank=1)
KW - Halitosis
KW - Laser
KW - Photodynamic therapy
KW - Tongue
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UR - http://www.scopus.com/inward/citedby.url?scp=84953358373&partnerID=8YFLogxK
U2 - 10.1007/s10103-015-1822-6
DO - 10.1007/s10103-015-1822-6
M3 - Article
C2 - 26510574
AN - SCOPUS:84953358373
SN - 0268-8921
VL - 31
SP - 41
EP - 47
JO - Lasers In Medical Science
JF - Lasers In Medical Science
IS - 1
ER -