Impact of cone-beam computed tomography scan mode on the diagnostic yield of chemically simulated external root resorption

Saulo L. Sousa Melo, Karla de Faria Vasconcelos, Nathan Holton, Veeratrishul Allareddy, Veerasathpurush Allareddy, Cinthia Pereira Machado Tabchoury, Francisco Haiter-Neto, Axel Ruprecht

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14 Scopus citations


Introduction The aim of this in-vitro study was to evaluate the influence of cone-beam computed tomography scans on the diagnosis of chemically simulated external root resorption. Methods One hundred extracted anterior teeth were selected. Subsurface demineralization was induced on a limited area of the apical third of the root of 49 teeth. Each tooth was placed in an empty socket of a partially edentulous dry mandible. Cone-beam computed tomography images were obtained according to 3 protocols: (1) half scan, 0.40-mm voxel size; (2) full scan, 0.40-mm voxel size; and (3) full scan, 0.125-mm voxel size. Three observers evaluated the images. Sensitivity, specificity, accuracy, and area under the curve were compared with the Cochran Q and Mann-Whitney U tests. Results Protocol 3 had the highest sensitivity (81.63%), accuracy (80.67%), and area under the curve (0.807). There were statistically significant differences between protocol 3 and the other 2 protocols (P <0.001). The specificity of protocol 1 (84.97%) was greater than that of protocols 2 (69.93%) and 3 (79.74%); however, a statistically significant difference was found only between protocols 1 and 2 (P = 0.005). Conclusions A more dedicated, high-resolution scan should be acquired when one intends to investigate the early stage of external root resorption during orthodontic treatment. However, this does not imply that all orthodontic patients should be subjected to high-dose cone-beam computed tomography scans.

Original languageEnglish (US)
Pages (from-to)1073-1082
Number of pages10
JournalAmerican Journal of Orthodontics and Dentofacial Orthopedics
Issue number6
StatePublished - Jun 2017
Externally publishedYes

ASJC Scopus subject areas

  • Orthodontics


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