TY - JOUR
T1 - Implementation of optical coherence tomography in retinopathy of prematurity screening
AU - Hanif, Adam M.
AU - Jian, Yifan
AU - Young, Benjamin K.
AU - Campbell, John Peter
N1 - Publisher Copyright:
© 2024 Lippincott Williams and Wilkins. All rights reserved.
PY - 2024/5/1
Y1 - 2024/5/1
N2 - Purpose of reviewIn this review, we explore the investigational applications of optical coherence tomography (OCT) in retinopathy of prematurity (ROP), the insights they have delivered thus far, and key milestones for its integration into the standard of care.Recent findingsWhile OCT has been widely integrated into clinical management of common retinal diseases, its use in pediatric contexts has been undermined by limitations in ergonomics, image acquisition time, and field of view. Recently, investigational handheld OCT devices have been reported with advancements including ultra-widefield view, noncontact use, and high-speed image capture permitting real-time en face visualization. These developments are compelling for OCT as a more objective alternative with reduced neonatal stress compared to indirect ophthalmoscopy and/or fundus photography as a means of classifying and monitoring ROP.SummaryOCT may become a viable modality in management of ROP. Ongoing innovation surrounding handheld devices should aim to optimize patient comfort and image resolution in the retinal periphery. Future clinical investigations may seek to objectively characterize features of peripheral stage and explore novel biomarkers of disease activity.
AB - Purpose of reviewIn this review, we explore the investigational applications of optical coherence tomography (OCT) in retinopathy of prematurity (ROP), the insights they have delivered thus far, and key milestones for its integration into the standard of care.Recent findingsWhile OCT has been widely integrated into clinical management of common retinal diseases, its use in pediatric contexts has been undermined by limitations in ergonomics, image acquisition time, and field of view. Recently, investigational handheld OCT devices have been reported with advancements including ultra-widefield view, noncontact use, and high-speed image capture permitting real-time en face visualization. These developments are compelling for OCT as a more objective alternative with reduced neonatal stress compared to indirect ophthalmoscopy and/or fundus photography as a means of classifying and monitoring ROP.SummaryOCT may become a viable modality in management of ROP. Ongoing innovation surrounding handheld devices should aim to optimize patient comfort and image resolution in the retinal periphery. Future clinical investigations may seek to objectively characterize features of peripheral stage and explore novel biomarkers of disease activity.
KW - biomarker
KW - optical coherence tomography
KW - retinopathy of prematurity
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U2 - 10.1097/ICU.0000000000001030
DO - 10.1097/ICU.0000000000001030
M3 - Review article
C2 - 38205941
AN - SCOPUS:85188690960
SN - 1040-8738
VL - 35
SP - 252
EP - 259
JO - Current opinion in ophthalmology
JF - Current opinion in ophthalmology
IS - 3
ER -