Inflammatory eye disease

James T. Rosenbaum, George N. Papaliodis

Research output: Chapter in Book/Report/Conference proceedingChapter


The eye is frequently the target of immune-mediated inflammation, either as the sole organ involved or as part of a multiorgan system disease. Systemic inflammatory disorders tend to involve the eye in characteristic manners. As examples, disorders associated with HLA-B27 often cause a highly symptomatic anterior uveitis; Behcet's disease can cause a subclinical but ultimately vision-threatening posterior uveitis; and Wegener's granulomatosis is associated with scleritis, peripheral ulcerative keratitis, and orbital pseudotumor. The diagnosis of systemic disease can therefore be inferred from the specific types of ocular involvement. The uveal tract is divided into anterior, intermediate, and posterior segments. "Anterior uveitis" and "iritis" are synonyms.

Original languageEnglish (US)
Title of host publicationA Clinician's Pearls and Myths in Rheumatology
PublisherSpringer London
Number of pages8
ISBN (Print)9781848009332
StatePublished - 2009

ASJC Scopus subject areas

  • General Medicine


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