Inflammatory vascular disease

Salil Gadkari, James T. Rosenbaum, Friederike MacKensen, Manfred Zierhut, Nicole Stübiger, Ina Kötter, Christoph Deuter, Matthias D. Becker, Ute Wiehler, Daniel W. Miller, Sobha Sivaprasad, Narciss Okhravi, Susan Lightman, Janet L. Davis, John J. Huang, C. Stephen Foster

Research output: Chapter in Book/Report/Conference proceedingChapter


Henry Eales, a British ophthalmologist, described this condition almost 125 years ago [14, 15]. Eales' original description was of recurring retinal and vitreous hemorrhages along with epistaxis, headaches, variation in peripheral circulation, dyspepsia, and chronic constipation in young men. He felt it was a vasomotor neurosis, wherein constriction of the alimentary vessels resulted in compensatory dilatation of the vessels in the head, leading to bleeding. Though Eales was honored with the eponym for this disease, Wadsworth was the first to describe the presence of retinal inflammation, 5 years later [37]. Duke Elder considered Eales' disease to be a clinical manifestation of many diseases.

Original languageEnglish (US)
Title of host publicationRetinal Vascular Disease
PublisherSpringer Berlin Heidelberg
Number of pages75
ISBN (Print)9783540295419
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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