Henry Eales, a British ophthalmologist, described this condition almost 125 years ago [14, 15]. Eales' original description was of recurring retinal and vitreous hemorrhages along with epistaxis, headaches, variation in peripheral circulation, dyspepsia, and chronic constipation in young men. He felt it was a vasomotor neurosis, wherein constriction of the alimentary vessels resulted in compensatory dilatation of the vessels in the head, leading to bleeding. Though Eales was honored with the eponym for this disease, Wadsworth was the first to describe the presence of retinal inflammation, 5 years later . Duke Elder considered Eales' disease to be a clinical manifestation of many diseases.
ASJC Scopus subject areas