Injection behaviors among injection drug users in treatment: The role of hepatitis C awareness

P. Todd Korthuis, Daniel J. Feaster, Zoilyn L. Gomez, Moupali Das, Susan Tross, Katharina Wiest, Antoine Douaihy, Raul N. Mandler, James L. Sorensen, Grant Colfax, Dennis McCarty, Stephanie E. Cohen, Patricia E. Penn, Diane Lape, Lisa R. Metsch

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background: Injection drug use (IDU) is a primary vector for blood-borne infections. Awareness of Hepatitis C virus (HCV) infection status may affect risky injection behaviors. This study determines the prevalence of risky injection practices and examines associations between awareness of positive HCV status and risky injection behaviors. Methods: We surveyed individuals seeking treatment for substance use at 12 community treatment programs as part of a national HIV screening trial conducted within the National Drug Abuse Treatment Clinical Trials Network. Participants reported socio-demographic characteristics, substance use, risk behaviors, and HCV status. We used multivariable logistic regression to test associations between participant characteristics and syringe/needle sharing. Results: The 1281 participants included 244 (19.0%) individuals who reported injecting drugs in the past 6. months and 37.7% of IDUs reported being HCV positive. During the six months preceding baseline assessment, the majority of IDUs reported obtaining sterile syringes from pharmacies (51.6%) or syringe exchange programs (25.0%), but fewer than half of IDUs always used a sterile syringe (46.9%). More than one-third (38.5%) shared syringe/needles with another injector in the past 6. months. Awareness of positive HCV vs. negative/unknown status was associated with increased recent syringe/needle sharing (aOR 2.37, 95% CI 1.15, 4.88) in multivariable analysis. Conclusions: Risky injection behaviors remain prevalent and awareness of HCV infection was associated with increased risky injection behaviors. New approaches are needed to broadly implement HCV prevention interventions for IDUs seeking addiction treatment.

Original languageEnglish (US)
Pages (from-to)552-555
Number of pages4
JournalAddictive Behaviors
Issue number4
StatePublished - Apr 2012


  • Alcoholism
  • Hepatitis C
  • Injection drug use
  • Opioid-related disorders
  • Syringe/needle sharing

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Toxicology
  • Psychiatry and Mental health


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