TY - JOUR
T1 - Interventional pulmonology approaches in the diagnosis and treatment of early stage non small cell lung cancer
AU - Tofts, Ryu Peter Hambrook
AU - Lee, Peter M.J.
AU - Sung, Arthur Wai
N1 - Publisher Copyright:
© Translational lung cancer research. All rights reserved.
PY - 2013
Y1 - 2013
N2 - Lung cancer management is complex and requires a multi-disciplinary approach to provide comprehensive care. Interventional pulmonology (IP) is an evolving field that utilizes minimally invasive modalities for the initial diagnosis and staging of suspected lung cancers. Endobronchial ultrasound guided sampling of mediastinal lymph nodes for staging and detection of driver mutations is instrumental for prognosis and treatment of early and later stage lung cancers. Advances in navigational bronchoscopy allow for histological sampling of suspicious peripheral lesions with minimal complication rates, as well as assisting with fiducial marker placements for stereotactic radiation therapy. Furthermore, IP can also offer palliation for inoperable cancers and those with late stage diseases. As the trend towards early lung cancer detection with low dose computed tomography is developing, it is paramount for the pulmonary physician with expertise in lung nodule management, minimally invasive sampling and staging to integrate into the paradigm of multi-specialty care.
AB - Lung cancer management is complex and requires a multi-disciplinary approach to provide comprehensive care. Interventional pulmonology (IP) is an evolving field that utilizes minimally invasive modalities for the initial diagnosis and staging of suspected lung cancers. Endobronchial ultrasound guided sampling of mediastinal lymph nodes for staging and detection of driver mutations is instrumental for prognosis and treatment of early and later stage lung cancers. Advances in navigational bronchoscopy allow for histological sampling of suspicious peripheral lesions with minimal complication rates, as well as assisting with fiducial marker placements for stereotactic radiation therapy. Furthermore, IP can also offer palliation for inoperable cancers and those with late stage diseases. As the trend towards early lung cancer detection with low dose computed tomography is developing, it is paramount for the pulmonary physician with expertise in lung nodule management, minimally invasive sampling and staging to integrate into the paradigm of multi-specialty care.
KW - Bronchoscopy
KW - Electromagnetic navigational bronchoscopy (ENB™)
KW - Gene expression profiling
KW - Interdisciplinary communication
KW - Radial probe-EBUS (RP-EBUS)
KW - TNM staging
KW - Virtual bronchoscopic navigation (VBN)
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U2 - 10.3978/j.issn.2218-6751.2013.10.11
DO - 10.3978/j.issn.2218-6751.2013.10.11
M3 - Review article
AN - SCOPUS:84904900596
SN - 2218-6751
VL - 2
SP - 316
EP - 331
JO - Translational Lung Cancer Research
JF - Translational Lung Cancer Research
IS - 5
ER -