Interventional pulmonology approaches in the diagnosis and treatment of early stage non small cell lung cancer

Ryu Peter Hambrook Tofts, Peter M.J. Lee, Arthur Wai Sung

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Lung cancer management is complex and requires a multi-disciplinary approach to provide comprehensive care. Interventional pulmonology (IP) is an evolving field that utilizes minimally invasive modalities for the initial diagnosis and staging of suspected lung cancers. Endobronchial ultrasound guided sampling of mediastinal lymph nodes for staging and detection of driver mutations is instrumental for prognosis and treatment of early and later stage lung cancers. Advances in navigational bronchoscopy allow for histological sampling of suspicious peripheral lesions with minimal complication rates, as well as assisting with fiducial marker placements for stereotactic radiation therapy. Furthermore, IP can also offer palliation for inoperable cancers and those with late stage diseases. As the trend towards early lung cancer detection with low dose computed tomography is developing, it is paramount for the pulmonary physician with expertise in lung nodule management, minimally invasive sampling and staging to integrate into the paradigm of multi-specialty care.

Original languageEnglish (US)
Pages (from-to)316-331
Number of pages16
JournalTranslational Lung Cancer Research
Volume2
Issue number5
DOIs
StatePublished - 2013
Externally publishedYes

Keywords

  • Bronchoscopy
  • Electromagnetic navigational bronchoscopy (ENB™)
  • Gene expression profiling
  • Interdisciplinary communication
  • Radial probe-EBUS (RP-EBUS)
  • TNM staging
  • Virtual bronchoscopic navigation (VBN)

ASJC Scopus subject areas

  • Oncology

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