Intraoperative optical imaging of human face cortical topography: A case study

Theodore H. Schwartz, Min Chen Li, Robert M. Friedman, Dennis D. Spencer, Anna W. Roe

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


We used intrinsic signal optical imaging to obtain maps of human somatosensory cortex during electrocutaneous stimulation of the face during a neurosurgical procedure for epilepsy. We found that human face somatotopy is organized like the macaque or cebus monkey, with peri-orbital skin located medial to peri-buccal skin, and that cortical magnification in the human is comparable to that in non-human primates. This study demonstrates that intrinsic signal imaging can be performed on humans during operative procedures with sufficient spatial resolution to reveal high-resolution topographic maps.

Original languageEnglish (US)
Pages (from-to)1527-1531
Number of pages5
Issue number9
StatePublished - Jun 28 2004
Externally publishedYes


  • Cerebral cortex
  • Cortical maps
  • Intrinsic signals
  • Neurosurgery
  • Somatosensory

ASJC Scopus subject areas

  • Neuroscience(all)


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