Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

Immunology and Microbiology

• Inflammation Response 100%
• Drug Megadose 100%
• Lung 100%
• Body Weight 66%
• Ribonucleic Acid 66%
• Ribosomal RNA 66%
• Ribosome RNA 66%
• Leukocyte 33%
• Cytokine 33%
• Chemokine 33%
• Capillary 33%
• Mitogen 33%
• Kidney Function 33%
• Fibrinogen 33%
• Fibrin 33%

Keyphrases

• High Dose 100%
• Systemic Inflammatory Response 100%
• Glomerular Injury 100%
• Ricin 100%
• Lung 30%
• Kidney 30%
• RNA Transcripts 20%
• Multiple Organs 20%
• 28S rRNA 20%
• Leukocytes 10%
• Kidney Function 10%
• Mitogen-activated Protein Kinase 10%
• Spleen 10%
• Inflammatory Response 10%
• Chemokines 10%
• Liver 10%
• Fibrin 10%
• Human Population 10%
• Fibrinogen 10%
• Glomerular Capillary 10%
• Fibrosis 10%
• Intratracheal Instillation 10%
• Pulmonary System 10%
• Circulating Cytokines 10%
• Bioweapons 10%
• Extrapulmonary Organs 10%
• Residual Damage 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Inflammation 100%
• RNA 28S 100%
• Cytokine 50%
• Mitogen Activated Protein Kinase 50%
• Chemokine 50%
• Fibrinogen 50%
• Fibrosis 50%
• Fibrin 50%