It takes two to tango, but three to ISA

Paco S. Herson; John P. Adelman

doi:10.1016/S0896-6273(03)00060-6

It takes two to tango, but three to I_SA

Paco S. Herson, John P. Adelman

Vollum Institute

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (I_SA) channels from rat cerebellum and identified a novel β subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.

Original language	English (US)
Pages (from-to)	370-372
Number of pages	3
Journal	Neuron
Volume	37
Issue number	3
DOIs	https://doi.org/10.1016/S0896-6273(03)00060-6
State	Published - Feb 6 2003

ASJC Scopus subject areas

General Neuroscience

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10.1016/S0896-6273(03)00060-6

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title = "It takes two to tango, but three to ISA",

abstract = "Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (ISA) channels from rat cerebellum and identified a novel β subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.",

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AU - Adelman, John P.

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N2 - Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (ISA) channels from rat cerebellum and identified a novel β subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.

AB - Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (ISA) channels from rat cerebellum and identified a novel β subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.

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It takes two to tango, but three to I_SA

Abstract

ASJC Scopus subject areas

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