It takes two to tango, but three to ISA

Paco S. Herson, John P. Adelman

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (ISA) channels from rat cerebellum and identified a novel β subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.

Original languageEnglish (US)
Pages (from-to)370-372
Number of pages3
Issue number3
StatePublished - Feb 6 2003
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)


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