ITF expression in mouse brain during acquisition of alcohol self-administration

Andrey E. Ryabinin, Ryan K. Bachtell, Pierre Freeman, Fred O. Risinger

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Expression of inducible transcription factors (ITFs) c-Fos and FosB was investigated during acquisition of alcohol drinking in C57BL/6J mice. A slight but statistically significant increase in c-Fos expression was found in the Edinger-Westphal nucleus (EW) of animals consuming 2% ethanol/10% sucrose for the first time. Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors.

Original languageEnglish (US)
Pages (from-to)192-195
Number of pages4
JournalBrain research
Issue number1
StatePublished - Jan 26 2001


  • Alcoholism
  • Edinger-Westphal
  • Immediate early gene

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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