Karyotypic analysis of a near diploid established mouse cell line

R. A. Farber, R. M. Liskay

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


A near diploid mouse cell line has been produced from C57BL/6J X AKR/J F1 hybrid embryonic cells by spontaneous transformation. The modal chromosome number of this line is 41 (2n = 40), with low numerical and structural variation relative to other mouse lines which have been reported. Giemsa banded karyotypes on a number of clones and subclones from this line have been analyzed. The most modal karyotypes deviate very little from that of a normal diploid female. Most of the cells have two X chromosomes, one of which is unlabeled early in the S phase.

Original languageEnglish (US)
Pages (from-to)384-396
Number of pages13
JournalCytogenetics and Cell Genetics
Issue number4
StatePublished - 1974

ASJC Scopus subject areas

  • Genetics
  • Cell Biology


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