@article{25647ee9b0af437cae84f92394221f06,
title = "Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines",
abstract = "Zhao et al. profile the protein responses of a large collection of cancer cell lines to drug perturbations using the RPPA platform and build a systematic protein-drug connectivity map. The integration of perturbed protein responses provides better prediction of drug sensitivity and insights into drug-resistance mechanisms and combination therapies.",
keywords = "biomarker, cancer signaling pathway, drug response, protein array",
author = "Wei Zhao and Jun Li and Chen, {Mei Ju M.} and Yikai Luo and Zhenlin Ju and Nesser, {Nicole K.} and Katie Johnson-Camacho and Boniface, {Christopher T.} and Yancey Lawrence and Pande, {Nupur T.} and Davies, {Michael A.} and Meenhard Herlyn and Taru Muranen and Zervantonakis, {Ioannis K.} and {von Euw}, Erika and Andre Schultz and Kumar, {Shwetha V.} and Anil Korkut and Spellman, {Paul T.} and Rehan Akbani and Slamon, {Dennis J.} and Gray, {Joe W.} and Brugge, {Joan S.} and Yiling Lu and Mills, {Gordon B.} and Han Liang",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = dec,
day = "14",
doi = "10.1016/j.ccell.2020.10.008",
language = "English (US)",
volume = "38",
pages = "829--843.e4",
journal = "Cancer Cell",
issn = "1535-6108",
publisher = "Cell Press",
number = "6",
}